Anatomical location and number of metastatic lymph nodes for prognosis of non-small cell lung cancer
نویسندگان
چکیده
منابع مشابه
Utility of Kynurenic Acid for Non-Invasive Detection of Metastatic Spread to Lymph Nodes in Non-Small Cell Lung Cancer
BACKGROUND Kynurenic acid (KYNA) is a side-stream product of the kynurenine metabolic pathway that plays a controversial role in malignancies either enabling escape of malignant cells from immune surveillance or exerting antiproliferative effect on cancer cells, and is associated with differences in invasiveness related to metastatic spread to lymph nodes in lung cancer. Nodal involvement is a ...
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BACKGROUND/AIM The aim of the study was to determine the pathways and expression profile of the genes that might predict response to neoadjuvant chemotherapy in patients with stage IIIA non-small cell lung cancer (NSCLC). MATERIALS AND METHODS We evaluated, by microarray, the gene-expression profile of tumoral mediastinal lymph node samples surgically removed from 27 patients with stage IIIA ...
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BACKGROUND c-MET has recently been identified as a promising novel target in non-small cell lung cancer (NSCLC). We detected the consistency of c-MET gene amplification in metastatic lymph nodes and tumor tissues of NSCLC patients and discuss the clinical application value of c-MET gene amplification in metastatic lymph nodes. METHODS Real-time fluorescent quantitative PCR was used to test tu...
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BACKGROUND Postoperative radiation (PORT) is an option for non-small cell lung cancer (NSCLC) patients with resectable stage IIIA pathological N2 status (pN2). For patients with PORT, this study aims to investigate the impact of the exact number of positive lymph nodes (LNs) on overall survival (OS) and lung cancer-specific survival (LCSS). METHODS Within the Surveillance, Epidemiology, and E...
متن کاملProposal of new nodal classifications for non-small-cell lung cancer based on the number and ratio of metastatic lymph nodes.
OBJECTIVE The study aimed to evaluate the effectiveness of two new nodal classifications based on the number of metastatic lymph nodes (LNs) or ratio of metastatic to examined LNs (LNR) in making a prognosis, compared with the current nodal classification based on the location of metastatic LNs. METHODS We analyzed 651 non-small-cell lung cancer patients who had undergone complete resection w...
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ژورنال
عنوان ژورنال: Journal of Thoracic Disease
سال: 2021
ISSN: 2072-1439,2077-6624
DOI: 10.21037/jtd-21-390